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TitleElectrospun polymeric dressings functionalized with antimicrobial peptides and collagen type I for enhanced wound healing
Author(s)Felgueiras, Helena Prado
Amorim, M. T. Pessoa de
KeywordsElectrospun wound dressings
Antimicrobial peptides
Collagen type I
Issue date14-Nov-2017
PublisherInstitute of Physics Publishing
JournalIOP Conference Series: Materials Science and Engineering
Abstract(s)Modern wound dressings combine medical textiles with active compounds that stimulate wound healing while protecting against infection. Electrospun wound dressings have been extensively studied and the electrospinning technique recognized as an efficient approach for the production of nanoscale fibrous mats. The unique diverse function and architecture of antimicrobial peptides (AMPs) has attracted considerable attention as a tool for the design of new anti-infective drugs. Functionalizing electrospun wound dressings with these AMPs is nowadays being researched. In the present work, we explore these new systems by highlighting the most important characteristics of electropsun wound dressings, revealing the importance of AMPs to wound healing, and the methods available to functionalize the electrospun mats with these molecules. The combined therapeutic potential of collagen type I and these AMP functionalized dressings will be highlighted as well; the significance of these new strategies for the future of wound healing will be clarified.
TypeConference paper
AccessOpen access
Appears in Collections:DET/2C2T - Artigos em revistas internacionais com arbitragem científica

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