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TitleInhibition of S. epidermidis adhesion to hydrogel contact lenses by anionic and nonionic surfactants
Author(s)Santos, Lívia
Oliveira, M. Elisabete
Oliveira, Rosário
Azeredo, Joana
Issue dateMar-2004
CitationEUROPEAN CONFERENCE ON BIOFILMS : PREVENTION OF MICROBIAL ADHESION, 1, Osnabrück, 2004 - "Proceedings of the 1st european conference on biofilms : prevention of microbial adhesion". [S.l. : s.n., 2004]. p. 62.
Abstract(s)In this study the adhesion of S. epidermidis to the 4 FDA groups of hydrogel CL uncoated and coated with ½ CMC of an anionic (sodium cholate) and a non-ionic surfactant (octylglucoside) was assessed. The results revealed that cell adhesion to CL was highly dependent on surface hydrophobicity. Concerning the effect of surfactants, the non-ionic one was more effective in inhibiting microbial adhesion than the ionic surfactant. Octylglucoside promoted an inhibition in the extent of bacterial adhesion of about 62%, while sodium cholate caused a decrease in the number of cells adhered of about 43%. The effect of a commercial multipurpose care solution containing 1% of poloxamine was compared and the results indicate that adhesion inhibition was greater when 0.33% of octylglucoside was used. Octylglucoside is a natural surfactant, non-toxic, harmless to the eye, and due to its high efficiency in inhibiting microbial adhesion, as proved in this work, is recommended to be incorporated in CL care solutions.
AccessOpen access
Appears in Collections:CEB - Resumos em Livros de Atas / Abstracts in Proceedings

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