Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/46544
Título: | Phage therapy as an alternative or complementary strategy to prevent and control biofilm-related infections |
Autor(es): | Pires, Diana P. Melo, Luís D. R. Boas, Diana Patrícia Andrade Vilas Sillankorva, Sanna Azeredo, Joana |
Data: | Out-2017 |
Editora: | Elsevier |
Revista: | Current Opinion in Microbiology |
Citação: | Pires, Diana P.; Melo, Luís D. R.; Vilas Boas, Diana; Sillankorva, Sanna; Azeredo, Joana, Phage therapy as an alternative or complementary strategy to prevent and control biofilm-related infections. Current Opinion in Microbiology, 39, 48-56, 2017 |
Resumo(s): | The complex heterogeneous structure of biofilms confers to bacteria an important survival strategy. Biofilms are frequently involved in many chronic infections in consequence of their low susceptibility to antibiotics as well as resistance to host defences. The increasing need of novel and effective treatments to target these complex structures has led to a growing interest on bacteriophages (phages) as a strategy for biofilm control and prevention. Phages can be used alone, as a cocktail to broaden the spectra of activity, or in combination with other antimicrobials to improve their efficacy. Here, we summarize the studies involving the use of phages for the treatment or prevention of bacterial biofilms, highlighting the biofilm features that can be tackled with phages or combined therapy approaches. |
Tipo: | Artigo |
URI: | https://hdl.handle.net/1822/46544 |
DOI: | 10.1016/j.mib.2017.09.004 |
ISSN: | 1369-5274 |
Arbitragem científica: | yes |
Acesso: | Acesso aberto |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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document_46988_1.pdf | 751,82 kB | Adobe PDF | Ver/Abrir |