Utilize este identificador para referenciar este registo: http://hdl.handle.net/1822/46126

TítuloSolid and aqueous magnetic liposomes as nanocarriers for a new potential drug active against breast cancer
Autor(es)Rodrigues, Ana Rita Oliveira
Silva, Pedro M. L.
Almeida, B. G.
Araújo, João P.
Queiroz, Maria João R. P.
Castanheira, Elisabete M. S.
Coutinho, Paulo J. G.
Palavras-chaveMagnetic nanoparticles
Drug delivery
Magnetoliposomes
New antitumor compounds
DataJan-2017
EditoraPhantoms Foundation
Resumo(s)In this work, iron oxide nanoparticles (NPs), with diameters around 12 nm, were synthesized by coprecipitation method. Both aqueous and solid magnetic liposomes containing magnetite NPs were obtained, with sizes below 140 nm. A new antitumor compound, a diarylurea derivative of thienopyridine, active against breast cancer, was incorporated in both aqueous and solid magnetoliposomes, being located mainly in the lipid membrane. A promising application of these magnetic liposomes in oncology is anticipated, allowing a combined therapeutic approach, using both chemotherapy and magnetic hyperthermia.
TipoconferenceAbstract
URIhttp://hdl.handle.net/1822/46126
Versão da editorahttp://www.nanopt.org/17EN/AbstractBooK.pdf
Arbitragem científicayes
AcessoopenAccess
Aparece nas coleções:CDQuim - Comunicações e Proceedings
CDF - FAMO - Comunicações/Communications (with refereeing)

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