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TitleMagnetogels based on iron oxide nanoparticles and peptide hydrogels containing Naproxen and/or RGD
Author(s)Magalhães, Carlos A. B.
Rodrigues, Ana Rita Oliveira
Almeida, B. G.
Martins, J. A.
Coutinho, Paulo J. G.
Araújo, João P.
Ferreira, Paula M. T.
Castanheira, Elisabete M. S.
KeywordsMagnetic nanoparticles
Drug nanocarriers
Targeted therapy
Issue dateJul-2017
Abstract(s)In this work, iron oxide nanoparticles, with diameters around 12 nm, were synthesized by coprecipitation method in aqueous solution. These nanoparticles exhibit a superparamagnetic behavior, with a coercive field of 9.7 Oe and a blocking temperature of 118 K. The nanoparticles were successfully incorporated in peptide-based hydrogels containing naproxen (Npx) and/or RGD. The ability of these magnetogels to act as drug nanocarriers is being investigated, aiming at developing multifunctional therapeutic nanosystems.
Publisher version
AccessOpen access
Appears in Collections:CDF - FAMO - Comunicações/Communications (with refereeing)

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