Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/44739

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dc.contributor.authorPinto, Graçapor
dc.contributor.authorSilva, Maria Danielapor
dc.contributor.authorPeddey, Markpor
dc.contributor.authorSillankorva, Sannapor
dc.contributor.authorAzeredo, Joanapor
dc.date.accessioned2017-02-13T15:35:25Z-
dc.date.issued2016-10-
dc.identifier.citationPinto, Graça; Silva, Maria Daniela; Peddey, Mark; Sillankorva, Sanna; Azeredo, Joana, The role of bacteriophages in periodontal health and disease. Future Microbiology, 11(10), 1359-1369, 2016por
dc.identifier.issn1746-0913por
dc.identifier.urihttp://hdl.handle.net/1822/44739-
dc.description.abstractThe human periodontium health is commonly compromised by chronic inflammatory conditions and has become a major public health concern. Dental plaque, the precursor of periodontal disease, is a complex biofilm consisting mainly of bacteria, but also archaea, protozoa, fungi and viruses. Viruses that specifically infect bacteria bacteriophages are most common in the oral cavity. Despite this, their role in the progression of periodontal disease remains poorly explored. This review aims to summarize how bacteriophages interact with the oral microbiota, their ability to increase bacterial virulence and mediate the transfer of resistance genes and suggests how bacteriophages can be used as an alternative to the current periodontal disease therapies.por
dc.description.sponsorshipThe authors thank the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit, COMPETE 2020 (POCI-01-0145-FEDER-006684) and by the Portuguese Foundation for Science and Technology (FCT) under the scope of the Project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462), and by the TecMinho, through the project 'Viral therapies for the control of anaerobic bacteria present in periodontal diseases' (TecMinho 045/TT/2014). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.por
dc.language.isoengpor
dc.publisherFuture Medicinepor
dc.rightsrestrictedAccesspor
dc.subjectbacteriophagepor
dc.subjectinteractionpor
dc.subjectmicrobiomepor
dc.subjectperiodontitispor
dc.subjecttherapypor
dc.titleThe role of bacteriophages in periodontal health and diseasepor
dc.typearticle-
dc.peerreviewedyespor
dc.relation.publisherversionhttp://www.futuremedicine.com/loi/fmbpor
dc.commentsCEB43173por
degois.publication.firstPage1359por
degois.publication.lastPage1369por
degois.publication.issue10por
degois.publication.locationUnited Kingdom-
degois.publication.titleFuture Microbiologypor
degois.publication.volume11por
dc.date.updated2017-02-04T17:17:38Z-
dc.identifier.essn1746-0921por
dc.identifier.doi10.2217/fmb-2016-0081por
dc.identifier.pmc27633580por
dc.subject.wosScience & Technologypor
sdum.journalFuture Microbiologypor
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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