Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/44739

TitleThe role of bacteriophages in periodontal health and disease
Author(s)Pinto, Graça
Silva, Maria Daniela
Peddey, Mark
Sillankorva, Sanna
Azeredo, Joana
Keywordsbacteriophage
interaction
microbiome
periodontitis
therapy
Issue dateOct-2016
PublisherFuture Medicine
JournalFuture Microbiology
CitationPinto, Graça; Silva, Maria Daniela; Peddey, Mark; Sillankorva, Sanna; Azeredo, Joana, The role of bacteriophages in periodontal health and disease. Future Microbiology, 11(10), 1359-1369, 2016
Abstract(s)The human periodontium health is commonly compromised by chronic inflammatory conditions and has become a major public health concern. Dental plaque, the precursor of periodontal disease, is a complex biofilm consisting mainly of bacteria, but also archaea, protozoa, fungi and viruses. Viruses that specifically infect bacteria bacteriophages are most common in the oral cavity. Despite this, their role in the progression of periodontal disease remains poorly explored. This review aims to summarize how bacteriophages interact with the oral microbiota, their ability to increase bacterial virulence and mediate the transfer of resistance genes and suggests how bacteriophages can be used as an alternative to the current periodontal disease therapies.
Typearticle
URIhttp://hdl.handle.net/1822/44739
DOI10.2217/fmb-2016-0081
ISSN1746-0913
e-ISSN1746-0921
Publisher versionhttp://www.futuremedicine.com/loi/fmb
Peer-Reviewedyes
AccessrestrictedAccess
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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