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TitleDifferences in dry eye questionnaire symptoms in two different modalities of contact lens wear: silicone-hydrogel in daily wear basis and overnight orthokeratology
Author(s)García-Porta, Nery
Rico-del-Viejo, L.
Martin-Gil, Alba
Carracedo, Gonzalo
Pintor, Jesús
González-Méijome, José Manuel
Issue date2016
PublisherHindawi Publishing Corporation
JournalBiomed Research International
CitationGarcia-Porta, N., Rico-del-Viejo, L., Martin-Gil, A., Carracedo, G., Pintor, J., & Gonzalez-Meijome, J. M. (2016). Differences in Dry Eye Questionnaire Symptoms in Two Different Modalities of Contact Lens Wear: Silicone-Hydrogel in Daily Wear Basis and Overnight Orthokeratology. BioMed Research International. doi: 10.1155/2016/1242845
Abstract(s)Purpose. To compare the ocular surface symptoms and signs in an adult population of silicone-hydrogel (Si-Hy) contact lens (CL) wearers with another modality of CL wear, overnight orthokeratology (OK). Materials and Methods. This was a prospective and comparative study in which 31 myopic subjects were fitted with the same Si-Hy CL and 23 underwent OK treatment for 3 months. Dry eye questionnaire (DEQ) was filled in at the beginning of the study and then after 15 days, 1 month, and 3 months using each CL modality. The tear quality was evaluated with noninvasive tear break-up time. Tear production was measured with Schirmer test. Tear samples were collected with Schirmer strips being frozen to analyze the dinucleotide diadenosine tetraphosphate (Ap4A) concentration with High-Performance Liquid Chromatography (HPLC). Results. After refitting with ortho-k, a reduction in discomfort and dryness symptoms at the end of the day (𝑝 < 0.05, 𝜒2 ) was observed. No significant changes were observed in Ap4A concentration in any group. Bulbar redness, limbal redness, and conjunctival staining increased significantly in the Si-Hy group (𝑝 < 0.05, Kruskal–Wallis test). Conclusion. Discomfort and dryness symptoms at the end of the day are lower in the OK CL group than in the Si-Hy CL group.
AccessOpen access
Appears in Collections:CDF - OCV - Artigos/Papers (with refereeing)

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