Please use this identifier to cite or link to this item:
|Title:||Cartilage tissue engineering and regenerative strategies|
|Author(s):||Morais, Alain José Silva|
Oliveira, J. M.
Reis, R. L.
|Publisher:||Springer International Publishing|
|Journal:||Studies in Mechanobiology Tissue Engineering and Biomaterials|
|Citation:||da Silva Morais A., Oliveira J. M., Reis R. L. Cartilage Tissue Engineering and Regenerative Strategies, Regenerative Strategies for the Treatment of Knee Joint Disabilities, Vol. 21, pp. 73-96, doi:10.1007/978-3-319-44785-8_5, 2017.|
|Abstract(s):||Human adult articular cartilage is a unique avascular tissue which displays the ability to resist to repetitive compressive stress. However, this connective tissue exhibits slight capacity for intrinsic restoration and, then even injuries or lesions can lead to progressive damage and osteoarthritic joint deterioration. Therefore, the field of cartilage repair continues to expand, bridging the gap between palliative care and chondral defects reconstruction. Tissue engineering strategy, centered on three actors: cells, proteins and scaffolds, received a lot of attention in the aim to develop an articular cartilage regeneration process that will be efficient, simple, and based on global market, costeffective. The current state of cartilage tissueÂ engineering with respect to different cellsources,Â growth factors and biomaterial scaffolds, as well as theÂ strategies employed in the restoration and repair of damaged articular cartilage will be the focus of thisÂ book chapter.|
|Access:||Restricted access (UMinho)|
|Appears in Collections:|
Files in This Item:
|791,26 kB||Adobe PDF||View/Open|