Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/43875

TitleNanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications
Author(s)Pereira, Eduardo Jorge Nunes
Silva, A. R.
Ribeiro, Clarisse
Carabineiro, S. A. C.
Buijnsters, J. G.
Lanceros-Méndez, S.
KeywordsNanodiamonds
poly(vinylidene fluoride)
Cell culture
Issue date15-Feb-2017
PublisherElsevier
JournalComposites Part B: Engineering
CitationJ. Nunes-Pereira; Silva, A. R.; Ribeiro, Clarisse; Carabineiro, S. A. C.; Buijnsters, J. G.; Lanceros-Méndez, S., Nanodiamonds/poly(vinylidene fluoride) composites for tissue engineering applications. Composites Part B: Engineering, 111, 37-44, 2017. doi: 10.1016/j.compositesb.2016.12.014
Abstract(s)Poly (vinylidene fluoride) (PVDF) composites with different types of nanodiamond (ND) particles were produced by solvent casting. The variations of the morphological, structural, optical, thermal and electrical properties of the composites were studied as a function of nanofiller type (without and with air oxidation treatment) and concentration (in the range 0.11 wt%). No noticeable differences were found in the polymer crystallization process, the processing conditions and the filler determining the morphology and structure of the polymer. Nevertheless, ND nanofillers were useful for the tailoring of the optical properties, and also slightly contributed to the thermodynamic stability of the samples. An increase in the dielectric constant (2) of the ND composites, while maintaining constant the dielectric losses, was observed, independently of the filler concentration. On the other hand, solvent casted porous composites crystallize mainly in the electroactive -phase of PVDF. Those composite membranes were evaluated with pre-osteoblast culture tests and these revealed that the inclusion of ND nanoparticles does not induce cytotoxicity on the samples. Taking advantage of the properties of the polymer for cell culture and with the potential of the ND filler for protein functionalization and drug delivery, it is concluded that NDs/PVDF composites are a suitable platform for biomedical applications.
TypeArticle
URIhttp://hdl.handle.net/1822/43875
DOI10.1016/j.compositesb.2016.12.014
ISSN1359-8368
Publisher versionhttp://www.journals.elsevier.com/composites-part-b-engineering
Peer-Reviewedyes
AccessRestricted access (UMinho)
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series
CDF - FCD - Artigos/Papers (with refereeing)

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