Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/43112

TitleNonlinear controller for bispectral index tracking: Robustness and on-line retuning
Author(s)Nogueira, Filipa Nunes
Mendonça, Teresa
Rocha, Paula
KeywordsAnesthesia
Automatic control
BIS
DoA
Positive systems
Robustness
Issue date2017
PublisherElsevier
JournalControl Engineering Practice
CitationNogueira F. N., Mendonça T., Rocha P. Nonlinear controller for bispectral index tracking: Robustness and on-line retuning, Control Engineering Practice, doi:10.1016/j.conengprac.2016.03.021, 2016
Abstract(s)In this paper, the performance of a control law designed for the automatic administration of propofol and of remifentanil in order to track a desired level for the bispectral index (BIS), used as a measure of the depth of anesthesia, is analyzed under the presence of model parameters uncertainties. It is theoretically proved and illustrated by simulations that under these circumstances the controller has a very good performance as the BIS converges to a value contained in a neighborhood of the desired BIS level. A retuning strategy in order to improve the BIS tracking under the presence of uncertainties was also theoretically deduced. Simulations show that this strategy leads to BIS tracking improvement. The performance of the controller in clinical environment is illustrated by a clinical case.
TypeArticle
DescriptionCorrected Proof
URIhttp://hdl.handle.net/1822/43112
DOI10.1016/j.conengprac.2016.03.021
ISSN0967-0661
Publisher versionhttp://www.sciencedirect.com/science/article/pii/S0967066116300612
Peer-Reviewedyes
AccessRestricted access (UMinho)
Appears in Collections:C-TAC - Artigos em Revistas Internacionais

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