Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/42196

TitleNovel strategies to fight Candida species infection
Author(s)Rodrigues, E.
Silva, Sónia Carina
Azeredo, Joana
Henriques, Mariana
KeywordsAntifungal agents
Immunotherapy
Low-level laser therapy
Natural compounds
Photodynamic
Issue date2016
PublisherInforma Healthcare
JournalCritical Reviews in Microbiology
CitationRodrigues, E.; Silva, Sónia Carina; Azeredo, Joana; Henriques, Mariana, Novel strategies to fight Candida species infection. Critical Reviews in Microbiology, 42(4), 594-606, 2016
Abstract(s)In recent years, there has been a significant increase in the incidence of human fungal infections. The increase in cases of infection caused by Candida species, and the consequent excessive use of antimicrobials, has favored the emergence of resistance to conventional antifungal agents over the past decades. Consequently, Candida infections morbidity and mortality are also increasing. Therefore, new approaches are needed to improve the outcome of patients suffering from Candida infections, because it seems unlikely that the established standard treatments will drastically lower the morbidity of mucocutaneous Candida infections and the high mortality associated with invasive candidiasis. This review aims to present the last advances in the traditional antifungal therapy, and present an overview of novel strategies that are being explored for the treatment of Candida infections, with a special focus on combined antifungal agents, antifungal therapies with alternative compounds (plant extracts and essential oils), adjuvant immunotherapy, photodynamic therapy and laser therapy.
TypeArticle
URIhttp://hdl.handle.net/1822/42196
DOI10.3109/1040841X.2014.974500
ISSN1040-841X
1549-7828
e-ISSN1549-7828
Publisher versionhttp://informahealthcare.com/journal/mby
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

Files in This Item:
File Description SizeFormat 
document_18496_1.pdf183,76 kBAdobe PDFView/Open

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID