Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/41548

TitlePrenatal dopamine and neonatal behavior and biochemistry
Author(s)Field, Tiffany
Diego, Miguel
Hernandez-Reif, Maria
Figueiredo, Bárbara
Deeds, Osvelia
Ascencio, Angela
Schanberg, Saul
Kuhn, Cynthia
Keywordsprenatal dopamine
depression
Issue dateDec-2008
PublisherElsevier
JournalInfant Behavior and Development
CitationInfant Behavior & Development 31 (2008) 590–593.
Abstract(s)Depressed pregnant women (N=126) were divided into high and low prenatal maternal dopamine (HVA) groups based on a tertile split on their dopamine levels at 20 weeks gestation. The high versus the low dopamine group had lower Center for Epidemiological Studies-Depression Scale (CES-D) scores, higher norepinephrine levels at the 20-week gestational age visit and higher dopamine and serotonin levels at both the 20- and the 32-week gestational age visits. The neonates of the mothers with high versus low prenatal dopamine levels also had higher dopamine and serotonin levels as well as lower cortisol levels. Finally, the neonates in the high dopamine group had better autonomic stability and excitability scores on the Brazelton Neonatal Behavior Assessment Scale. Thus, prenatal maternal dopamine levels appear to be negatively related to prenatal depression scores and positively related to neonatal dopamine and behavioral regulation, although these effects are confounded by elevated serotonin levels.
TypeArticle
URIhttp://hdl.handle.net/1822/41548
DOI10.1016/j.infbeh.2008.07.007
ISSN0163-6383
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CIPsi - Artigos (Papers)

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