Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/40927

Full metadata record
DC FieldValueLanguage
dc.contributor.authorNeves, Lisete S.por
dc.contributor.authorRodrigues, Márcia T.por
dc.contributor.authorReis, R. L.por
dc.contributor.authorGomes, Manuela E.por
dc.date.accessioned2016-03-24T11:19:45Z-
dc.date.available2016-03-24T11:19:45Z-
dc.date.issued2016-
dc.identifier.citationNeves L. S., Rodrigues M. T., Reis R. L., Gomes M. E. Current approaches and future perspectives on strategies for the development of personalized tissue engineering therapies, Personalized medicine in drug development and clinical practice, Vol. 1, pp. 93–108, doi:10.1080/23808993.2016.1140004, 2016por
dc.identifier.issn2380-8993por
dc.identifier.urihttp://hdl.handle.net/1822/40927-
dc.description.abstractPersonalized tissue engineering and regenerative medicine (TERM) therapies propose patient-oriented effective solutions, considering individual needs. Cell-based therapies, for example, may benefit from cell sources that enable easier autologous set-ups or from recent developments on IPS cells technologies towards effective personalized therapeutics. Furthermore, the customization of scaffold materials to perfectly fit a patientâ s tissue defect through rapid prototyping technologies, also known as 3D printing, is now a reality. Nevertheless, the timing to expand cells or to obtain functional in vitrotissue substitutes prior to implantation prevents advancements towards routine use upon patient´s needs. Thus, personalized therapies also anticipate the importance of creating off-the-shelf solutions to enable immediately available tissue engineered products. This paper reviews the main recent developments and future challenges to enable personalized TERM approaches and to bring these technologies closer to clinical applications.por
dc.description.sponsorshipThe authors wish to acknowledge the financial support of the Portuguese Foundation for Science and Technology for the post-doctoral grant (SFRH/BPD/111729/2015) and Recognize (UTAP-ICDT/CTM-BIO/0023/2014), and the project RL3 -TECT -NORTE-07-0124-FEDER-000020 co-financed by ON.2 (NSRF), through ERDF.por
dc.language.isoengpor
dc.publisherTaylor & Francispor
dc.relationinfo:eu-repo/grantAgreement/FCT/3599-PPCDT/137422/PTpor
dc.rightsopenAccesspor
dc.subjectCell therapiespor
dc.subjectCryo-bankingpor
dc.subjectCryopreservationpor
dc.subjectCustomizationpor
dc.subjectOff-the-shelfpor
dc.subjectPersonalized medicinepor
dc.subjectTissue engineeringpor
dc.subjectTranslational platformspor
dc.titleCurrent approaches and future perspectives on strategies for the development of personalized tissue engineering therapiespor
dc.typearticle-
dc.peerreviewednopor
dc.relation.publisherversionhttp://www.tandfonline.com/doi/abs/10.1080/23808993.2016.1140004por
dc.commentshttp://3bs.uminho.pt/node/18689por
sdum.publicationstatuspublishedpor
oaire.citationStartPage93por
oaire.citationEndPage108por
oaire.citationIssue1por
oaire.citationTitleExpert review of precision medicine and drug development: personalized medicine in drug development and clinical practicepor
oaire.citationVolume1por
dc.date.updated2016-03-18T11:53:34Z-
dc.identifier.doi10.1080/23808993.2016.1140004por
dc.subject.wosScience & Technologypor
sdum.journalExpert Review of Precision Medicine and Drug Development: Personalized Medicine in Drug Development and Clinical Practicepor
Appears in Collections:3B’s - Artigos em revistas/Papers in scientific journals


Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID