Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/40515

TitleEscherichia coli and Enterococcus faecalis are able to incorporate and enhance a pre-formed Gardnerella vaginalis biofilm
Author(s)Castro, Joana
Machado, D.
Cerca, Nuno
KeywordsUrinary tract infection
Bacterial vaginosis
Uropathogens
Mixed biofilms
Issue dateApr-2016
PublisherWiley
JournalPathogens and Disease
CitationCastro, J.; Machado, D.; Cerca N, Escherichia coli and Enterococcus faecalis are able to incorporate and enhance a pre-formed Gardnerella vaginalis biofilm. Pathogens and Disease, 74(3), ftw007, 2016
Abstract(s)Gardnerella vaginalis is the most frequent microorganism found in bacterial vaginosis (BV), while Escherichia coli and Enterococcus faecalis are amongst the most frequent pathogens found in urinary tract infections (UTIs). This study aimed to evaluate possible interactions between UTIs pathogens and G. vaginalis using an in vitro dual-species biofilm model. Our results showed that dual-species biofilms reached significantly higher bacterial concentration than mono-species biofilms. Moreover, visualization of dual-populations species in the biofilms, using the epifluorescence microscopy, revealed that all of the urogenital pathogens co-existed with G. vaginalis. In conclusion, our work demonstrates that uropathogens can incorporate into mature BV biofilms.
TypeArticle
URIhttp://hdl.handle.net/1822/40515
DOI10.1093/femspd/ftw007
ISSN2049-632X
e-ISSN2049-632X
Publisher versionhttp://onlinelibrary.wiley.com/journal/10.1111/(ISSN)2049-632X
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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