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TitleProving the suitability of magnetoelectric stimuli for tissue engineering applications
Author(s)Ribeiro, C.
Correia, Vítor Manuel Gomes
Martins, P.
Gama, F. M.
Lanceros-Méndez, S.
KeywordsBone tissue engineering
Cell proliferation
Magnetic stimulus
Issue dateApr-2016
PublisherElsevier B.V.
JournalColloids and Surfaces B: Biointerfaces
CitationRibeiro, C.; Correia, V.; Martins, P.; Gama, F. M.; Lanceros-Mendez, S., Proving the suitability of magnetoelectric stimuli for tissue engineering applications. Colloids and Surfaces B: Biointerfaces, 140, 430-436, 2016
Abstract(s)A novel approach for tissue engineering applications based on the use of magnetoelectric materials is presented. This work proves that magnetoelectric Terfenol-D/poly(vinylidene fluoride-co-trifluoroethylene) composites are able to provide mechanical and electrical stimuli to MC3T3-E1 pre-osteoblast cells and that those stimuli can be remotely triggered by an applied magnetic field. Cell proliferation is enhanced up to 25% when cells are cultured under mechanical (up to 110 ppm) and electrical stimulation (up to 0.115 mV), showing that magnetoelectric cell stimulation is a novel and suitable approach for tissue engineering allowing magnetic, mechanical and electrical stimuli.
Publisher version
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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