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TitleSustained effects of a neural-based intervention in a refractory case of Tourette syndrome
Author(s)Carvalho, Sandra Conceição Ribeiro
Gonçalves, Óscar F.
Soares, José Miguel
Sampaio, Adriana
Macedo, Fernando
Fregni, Felipe
Leite, Jorge
Issue date2015
JournalBrain stimulation
CitationCarvalho, S., Gonçalves, Ó. F., Soares, J. M., Sampaio, A., Macedo, F., Fregni, F., & Leite, J. (2015). Sustained Effects of a Neural-based Intervention in a Refractory Case of Tourette Syndrome. Brain Stimulation. doi: 10.1016/j.brs.2014.12.008
Abstract(s)There are only a few treatments available for Tourette syndrome (TS). These treatments frequently do notwork in patients with moderate to severe TS [1]. Neuroimaging studies show a correlation between tics severity and increased activation over motor pathways, along with reduced activation over the control areas of the cortico-striato-thalamo-cortical circuits [2]. Moreover, the temporal pattern of tic generation suggests that cortical activation especially in the SMA precedes subcortical activation [3]. Following this assumption, here we explored the brain effects of 10-daily sessions of cathodal transcranial Direct Current Stimulation (tDCS) delivered over the pre-SMA in a patient with refractory and severe TS and also assessed whether those changes were long lasting (up to 6 months).
TypeLetter to the editor
Description[Letter to the editor]
AccessRestricted access (UMinho)
Appears in Collections:CIPsi - Artigos (Papers)

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