Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/40130

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dc.contributor.authorAlves, Jorgepor
dc.contributor.authorMagalhães, Rosanapor
dc.contributor.authorArantes, Mavildepor
dc.contributor.authorCruz, Sarapor
dc.contributor.authorGonçalves, Óscar F.por
dc.contributor.authorSampaio, Adrianapor
dc.date.accessioned2016-02-05T14:40:05Z-
dc.date.issued2015-
dc.date.submitted2013-
dc.identifier.citationAlves, J., Magalhaes, R., Arantes, M., Cruz, S., Goncalves, O. F., & Sampaio, A. (2015). Cognitive Rehabilitation in a Visual Variant of Alzheimer's Disease. Applied Neuropsychology-Adult, 22(1), 73-78. doi: 10.1080/23279095.2013.831865por
dc.identifier.issn2327-9095por
dc.identifier.issn2327-9109por
dc.identifier.urihttp://hdl.handle.net/1822/40130-
dc.description.abstractAlzheimer's disease (AD) is commonly associated with marked memory deficits; however, nonamnestic variants have been consistently described as well. Posterior cortical atrophy (PCA) is a progressive degenerative condition in which posterior regions of the brain are predominantly affected, therefore resulting in a pattern of distinctive and marked visuospatial symptoms, such as apraxia, alexia, and spatial neglect. Despite the growing number of studies on cognitive and neural bases of the visual variant of AD, intervention studies remain relatively sparse. Current pharmacological treatments offer modest efficacy. Also, there is a scarcity of complementary nonpharmacological interventions with only two previous studies of PCA. Here we describe a highly educated 57-year-old patient diagnosed with a visual variant of AD who participated in a cognitive intervention program (comprising reality orientation, cognitive stimulation, and cognitive training exercises). Neuropsychological assessment was performed across moments (baseline, postintervention, follow-up) and consisted mainly of verbal and visual memory. Baseline neuropsychological assessment showed deficits in perceptive and visual-constructive abilities, learning and memory, and temporal orientation. After neuropsychological rehabilitation, we observed small improvements in the patient's cognitive functioning, namely in verbal memory, attention, and psychomotor abilities. This study shows evidence of small beneficial effects of cognitive intervention in PCA and is the first report of this approach with a highly educated patient in a moderate stage of the disease. Controlled studies are needed to assess the potential efficacy of cognition-focused approaches in these patients, and, if relevant, to grant their availability as a complementary therapy to pharmacological treatment and visual aids.por
dc.description.sponsorshipThis work was supported by the Portuguese Foundation for Science and Technology with individual grants (SFRH=BD=64457=2009, SFRH=BD=65213=2009, cofunded by FSE=POPH) and project grant PIC=IC=83290= 2007, supported by FEDER (POFC–COMPETE)por
dc.language.isoengpor
dc.publisherRoutledgepor
dc.relationSFRH/BD/64457/2009por
dc.relationSFRH/BD/65213/2009por
dc.relationinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/83290/PTpor
dc.rightsrestrictedAccesspor
dc.subjectAlzheimer diseasepor
dc.subjectAttentionpor
dc.subjectCognitionpor
dc.subjectHumanspor
dc.subjectMalepor
dc.subjectMemorypor
dc.subjectMiddle Agedpor
dc.subjectNeuropsychological testspor
dc.subjectcognitive rehabilitationpor
dc.subjectposterior cortical atrophypor
dc.subjectcognitive interventionpor
dc.subjectAlzheimer's diseasepor
dc.titleCognitive rehabilitation in a visual variant of Alzheimer's diseasepor
dc.typearticlepor
dc.peerreviewedyespor
sdum.publicationstatuspublishedpor
oaire.citationStartPage73por
oaire.citationEndPage78por
oaire.citationIssue1por
oaire.citationTitleApplied neuropsychology. Adultpor
oaire.citationVolume22por
dc.identifier.doi10.1080/23279095.2013.831865por
dc.identifier.pmid25529594por
dc.subject.wosScience & Technologypor
dc.subject.wosSocial Sciencespor
sdum.journalApplied Neuropsychology. Adultpor
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