The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds

doi:10.1016/j.indcrop.2015.05.086

Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/39809

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Campo DC	Valor	Idioma
dc.contributor.author	Barros, Lillian	por
dc.contributor.author	Calhelha, Ricardo C.	por
dc.contributor.author	Queiroz, Maria João R. P.	por
dc.contributor.author	Santos-Buelga, Celestino	por
dc.contributor.author	Santos, E.A.	por
dc.contributor.author	Regis, W.C.B.	por
dc.contributor.author	Ferreira, Isabel C. F. R.	por
dc.date.accessioned	2016-01-31T22:41:59Z	-
dc.date.available	2016-01-31T22:41:59Z	-
dc.date.issued	2015-07	-
dc.date.submitted	2015-01	-
dc.identifier.citation	Barros, L., Calhelha, R. C., Queiroz, M. J. R. P., Santos-Buelga, C., Santos, E. A., Regis, W. C. B., & Ferreira, I. C. F. R. (2015). The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds. Industrial Crops and Products, 76, 318-322. doi: 10.1016/j.indcrop.2015.05.086	por
dc.identifier.issn	0926-6690	-
dc.identifier.uri	https://hdl.handle.net/1822/39809	-
dc.description.abstract	The Euterpe oleracea Mart. (açaí) is a plant from the Amazon region, classified as "super fruit" because of its various functional properties. However, limited investigation has been performed on açaí by-products, such as seeds. Therefore, the aim of this work was to characterized the phenolic compounds of the aqueous extract of açaí seeds and further evaluate its bioactivity (antioxidant and cytotoxic activities. Only proanthocyanidins were detected, being a B-type (epi)catechin tetramer the most abundant; however, procyanidin trimmers were the most predominant form. Açaí seeds extract revealed a high antioxidant (EC50 ranging from 3.6 to 19.4 μg/mL) and cytotoxic activity, being more effective in the cervical carcinoma cell line (HeLa; GI50 = 18 μg/mL); it did not show toxicity for non-tumor cells. Açaí seeds are considered a waste and could have an added economic benefit, through the extraction of natural antioxidants, particularly proanthocyanidins, that could find applications in food and pharmaceutical industries.	por
dc.description.sponsorship	The authors are grateful to Foundation for Science and Technology (FCT, Portugal) for financial support to the research centre CIMO (strategic project PEst OE/AGR/UI0690/2011) and L. Barros researcher contract under “Programa Compromisso com Ciência - 2008”. The authors are also grateful to Jamil S. Oliveira by the initial discussions on the preparation of samples.	por
dc.language.iso	eng	por
dc.publisher	Elsevier	por
dc.relation	Pest OE/AGR/UI0690/2011	por
dc.rights	openAccess	por
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	por
dc.subject	Euterpe oleracea	por
dc.subject	Phenolic characterization	por
dc.subject	Antioxidant properties	por
dc.subject	Antitumor activity	por
dc.title	The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds	por
dc.type	article	por
dc.peerreviewed	yes	por
dc.relation.publisherversion	http://dx.doi.org/10.1016/j.indcrop.2015.05.086	por
sdum.publicationstatus	published	por
oaire.citationStartPage	318	por
oaire.citationEndPage	322	por
oaire.citationTitle	Industrial Crops and Products	por
oaire.citationVolume	76	por
dc.identifier.doi	10.1016/j.indcrop.2015.05.086	por
dc.subject.fos	Ciências Agrárias::Outras Ciências Agrárias	por
dc.subject.fos	Ciências Naturais::Ciências Químicas	por
dc.subject.wos	Science & Technology	por
sdum.journal	Industrial Crops and Products	por
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