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TitlePhage therapy: a step forward in the treatment of Pseudomonas aeruginosa infections
Author(s)Pires, Diana
Boas, Diana Patrícia Andrade Vilas
Sillankorva, Sanna
Azeredo, Joana
Issue date2015
PublisherAmerican Society for Microbiology (ASM)
JournalJournal of Virology
CitationPires, Diana; Vilas Boas, Diana; Sillankorva, Sanna; Azeredo, Joana, Phage therapy: a step forward in the treatment of Pseudomonas aeruginosa infections. Journal of Virology, 89(15), 7449-7456, 2015
Abstract(s)Antimicrobial resistance constitutes one of the major worldwide public health concerns. Bacteria are becoming resistant to the vast majority of antibiotics and nowadays, a common infection can be fatal. To revert this situation, the use of phages for the treatment of bacterial infections has been extensively studied as an alternative therapeutic strategy. Since P. aeruginosa is one of the most common causes of healthcare-associated infections, many studies have reported the in vitro and in vivo antibacterial efficacy of phage therapy against this bacterium. This review collects data of all the P. aeruginosa phages sequenced to date, providing a better understanding about their biodiversity. This review will further address the in vitro and in vivo results obtained by using phages to treat or prevent P. aeruginosa infections as well as the major hurdles associated with this therapy.
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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