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TitleDesign and fabrication of SiO2/TiO2 and MgO/TiO2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction
Author(s)Pimenta, Sara
Cardoso, S.
Miranda, A.
De Beule, P.
Castanheira, Elisabete M. S.
Minas, Graça
Optical filters
Gastrointestinal cancer
Early detection
Medical optics instrumentation
Tissue diagnostics
Deposition and fabrication
Materials and process characterization
Spectroscopy, tissue diagnostics
Issue date1-Aug-2015
PublisherOptical Society of America
JournalBiomedical Optics Express
CitationPimenta, S., Cardoso, S., Miranda, A., De Beule, P., Castanheira, E. M. S., & Minas, G. (2015). Design and fabrication of SiO 2/TiO 2 and MgO/TiO 2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction. Biomedical optics express, 6(8), 3084-3098
Abstract(s)This paper presents the design, optimization and fabrication of 16 MgO/TiO2 and SiO2/TiO2 based high selective narrow bandpass optical filters. Their performance to extract diffuse reflectance and fluorescence signals from gastrointestinal tissue phantoms was successfully evaluated. The obtained results prove their feasibility to correctly extract those spectroscopic signals, through a Spearman’s rank correlation test (Spearman’s correlation coefficient higher than 0.981) performed between the original spectra and the ones obtained using those 16 fabricated optical filters. These results are an important step for the implementation of a miniaturized, low-cost and minimal invasive microsystem that could help in the detection of gastrointestinal dysplasia.
Publisher version
AccessOpen access
Appears in Collections:CDF - FAMO - Artigos/Papers (with refereeing)
DEI - Artigos em revistas internacionais

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