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TitlePeptide-induced permeation of model membranes by antimicrobial peptidomimetics
Author(s)Carvalho, Carina Martins
Castro, Vânia I. B.
Pereira-Lima, Sílvia M. M. A.
Costa, Susana P. G.
Castanheira, Elisabete M. S.
KeywordsAntimicrobial peptides
Model membranes
Issue dateJul-2015
Abstract(s)In the present communication, a set of Peptaibolin and several peptidomimetics incorporating unnatural α,α-dialkylglycines (Deg, Dpg, Ac6c) were studied for their ability to interact and permeate model membranes from phosphatidylcholine/cholesterol, in different ratios. The permeation activity was monitored by fluorescence spectroscopy, following the release of encapsulated 6-carboxyfluorescein.
Publisher versionRICI6 Abstracts Book
AccessOpen access
Appears in Collections:CDF - FAMO - Comunicações/Communications (with refereeing)
CDQuim - Artigos (Papers)

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