Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/37012

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dc.contributor.authorRibeiro, V. P.por
dc.contributor.authorAlmeida, L. R.por
dc.contributor.authorMartins, A. R.por
dc.contributor.authorPashkuleva, I.por
dc.contributor.authorMarques, A. P.por
dc.contributor.authorRibeiro, Ana S.por
dc.contributor.authorSilva, Carla J. S. M.por
dc.contributor.authorBonifácio, Graçapor
dc.contributor.authorSousa, R. A.por
dc.contributor.authorReis, R. L.por
dc.contributor.authorOliveira, A. L.por
dc.date.accessioned2015-09-10T11:08:48Z-
dc.date.available2015-09-10T11:08:48Z-
dc.date.issued2016-
dc.date.submitted2014-07-
dc.identifier.citation105. Ribeiro, V. P., Almeida, L. R., Martins, A. R., Pashkuleva, I., Marques, A. P., Ribeiro, A. S., . . . Oliveira, A. L. (2016). Influence of different surface modification treatments on silk biotextiles for tissue engineering applications. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 104(3), 496-507. doi: 10.1002/jbm.b.33400por
dc.identifier.issn1552-4981por
dc.identifier.urihttp://hdl.handle.net/1822/37012-
dc.description.abstractBiotextile structures from silk fibroin have demonstrated to be particularly interesting for tissue engineering (TE) applications due to their high mechanical strength, interconnectivity, porosity, and ability to degrade under physiological conditions. In this work, we described several surface treatments of knitted silk fibroin (SF) scaffolds, namely sodium hydroxide (NaOH) solution, ultraviolet radiation exposure in an ozone atmosphere (UV/O3) and oxygen (O2) plasma treatment followed by acrylic acid (AAc), vinyl phosphonic acid (VPA), and vinyl sulfonic acid (VSA) immersion. The effect of these treatments on the mechanical properties of the textile constructs was evaluated by tensile tests in dry and hydrated states. Surface properties such as morphology, topography, wettability and elemental composition were also affected by the applied treatments. The in vitro biological behavior of L929 fibroblasts revealed that cells were able to adhere and spread both on the untreated and surface-modified textile constructs. The applied treatments had different effects on the scaffoldsâ surface properties, confirming that these modifications can be considered as useful techniques to modulate the surface of biomaterials according to the targeted application.por
dc.description.sponsorshipContract grant sponsor: Portuguese Foundation for Science and Technology under POCTI and/or FEDER programs under the scope of the project TISSUE2TISSUE; contract grant number: PTDC/CTM/105703/2008Contract grant sponsor: Investigator FCT program (to A.N.L.); contract grant number: IF/00411/2013por
dc.language.isoengpor
dc.publisherJohn Wiley and Sonspor
dc.rightsopenAccesspor
dc.subjectBiotextilepor
dc.subjectScaffoldpor
dc.subjectSilk fibroinpor
dc.subjectSurface modificationpor
dc.subjectTissue engineeringpor
dc.titleInfluence of different surface modification treatments on silk biotextiles for tissue engineering applicationspor
dc.typearticle-
dc.peerreviewedyespor
dc.relation.publisherversionhttp://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33400/fullpor
dc.commentshttp://www.3bs.uminho.pt/node/18352por
sdum.publicationstatuspublishedpor
oaire.citationStartPage1por
oaire.citationEndPage12por
oaire.citationIssue3por
oaire.citationTitleJournal of Biomedical Materials Research Part B: Applied Biomaterialspor
oaire.citationVolume104por
dc.date.updated2015-08-05T14:53:55Z-
dc.identifier.doi10.1002/jbm.b.33400por
dc.identifier.pmid25939722por
dc.subject.fosEngenharia e Tecnologia::Engenharia dos Materiaispor
dc.subject.fosCiências Médicas::Biotecnologia Médicapor
dc.subject.wosScience & Technologypor
sdum.journalJournal of Biomedical Materials Research Part Bpor
Appears in Collections:3B’s - Artigos em revistas/Papers in scientific journals


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