Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/3646

TitleDecalactone production by Yarrowia lipolytica under increased O2 transfer rates
Author(s)Aguedo, Mário
Gomes, Nelma
Escamilla Garcia, Erandi
Waché, Yves
Mota, M.
Teixeira, J. A.
Belo, Isabel
KeywordsB-oxidation
Decalactones
O2
Pressure
Yarrowia lipolytica
β-oxidation
Issue dateOct-2005
PublisherSpringer
JournalBiotechnology letters
Citation"Biotechnology letters". ISSN 0141-5492. 27:20 (Oct. 2005) 1617-1621.
Abstract(s)Yarrowia lipolytica converts methyl ricinoleate to γ-decalactone, a high-value fruity aroma compound. The highest amount of 3-hydroxy-γ-decalactone produced by the yeast (263 mg lˉ¹) occurred by increasing the kLa up to 120 hˉ¹ at atmospheric pressure; above it, its concentration decreased, suggesting a predominance of the activity of 3- ydroxyacyl-CoA dehydrogenase. Cultures were grown under high-pressure, i.e., under increased O2 solubility, but, although growth was accelerated, γ-decalactone production decreased. However, by applying 0.5 MPa during growth and biotransformation gave increased oncentrations of dec-2-en-4-olide and dec-3-en-4-olide (70 mg lˉ¹).
TypeArticle
URIhttp://hdl.handle.net/1822/3646
DOI10.1007/s10529-005-2517-z
ISSN0141-5492
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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