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dc.contributor.authorSilveira, Henrique C. S.por
dc.contributor.authorCarrijo, Marina Schmidtpor
dc.contributor.authorSeidel, Ervald Henriquepor
dc.contributor.authorNeto, Cristovam Scapulatempopor
dc.contributor.authorLongatto Filho, Adhemarpor
dc.contributor.authorCarvalho, André Lopespor
dc.contributor.authorReis, R. M.por
dc.contributor.authorSaldiva, Paulo Hilário Nascimentopor
dc.description.abstractBackground: To determine the possible genotoxic effect of exposure to the smoke generated by biomass burning on workers involved in manual sugar cane harvesting. Methods: The frequency of micronuclei in exfoliated buccal cells and peripheral blood lymphocytes was determined in sugarcane workers in the Barretos region of Brazil, during the harvest season and compared to a control population, comprised of administrative employees of Barretos Cancer Hospital. Results: The frequency of micronuclei was higher in the sugar cane workers. The mean frequency in blood lymphocytes (micronuclei/1000 cells) in the test group was 8.22 versus 1.27 in the control group. The same effect was observed when exfoliated buccal cells were considered (22.75 and 9.70 micronuclei/1000 cells for sugar cane workers and controls, respectively). Conclusion: Exposure to emissions produced by the burning of sugar cane during harvesting induces genomic instability in workers, indicating the necessity of adopting more advanced techniques of harvesting sugar cane to preserve human health.por
dc.description.sponsorshipWe thank the Researcher Support Center of Barretos Cancer Hospital, especially the statistician Zanardo C. for assisting in the statistical analysis. We thank Oliveira R. for technical support, and we acknowledge financial support from FAPESP Proc. 2010/10192-6.por
dc.publisherBioMed Central (BMC)por
dc.subjectSugar cane workerspor
dc.subjectGenomic instabilitypor
dc.subjectHuman lymphocytespor
dc.subjectExfoliated buccal cellspor
dc.titleEmissions generated by sugarcane burning promote genotoxicity in rural workers: a case study in Barretos, Brazilpor
oaire.citationTitleEvironmental Healthypor
dc.subject.wosScience & Technologypor
sdum.journalEvironmental Healthypor
Appears in Collections:ICVS - Artigos em Revistas Internacionais com Referee

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