Utilize este identificador para referenciar este registo: https://hdl.handle.net/1822/33446

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dc.contributor.authorScuteri, Angelopor
dc.contributor.authorCunha, Pedro Guimarãespor
dc.contributor.authorRosei, E. Agabitipor
dc.contributor.authorBekaert, Sofiepor
dc.contributor.authorCockcrofti, John R.por
dc.contributor.authorCotter, Jorgepor
dc.contributor.authorCucca, Francescopor
dc.contributor.authorDe Buyzere, Marc L.por
dc.contributor.authorDe Meyer, Timpor
dc.contributor.authorFerrucci, Luigipor
dc.contributor.authorFranco, Francopor
dc.contributor.authorGale, Nicholspor
dc.contributor.authorGillebert, Thierry C.por
dc.contributor.authorHofman, A.por
dc.contributor.authorLanglois, Michelpor
dc.contributor.authorLaucevicius, Aleksandraspor
dc.contributor.authorLaurent, Stephanepor
dc.contributor.authorRaso, Francesco U.S. Mattacepor
dc.contributor.authorMorrell, Cristopher H.por
dc.contributor.authorMuiesan, Maria Lorenzapor
dc.contributor.authorMunnery, Margaret M.por
dc.contributor.authorNavickas, Rokaspor
dc.contributor.authorOliveira, Pedropor
dc.contributor.authorOrru, Marcopor
dc.contributor.authorPilia, Maria Graziapor
dc.contributor.authorRietzschel, Ernst R.por
dc.contributor.authorRyliskyte, Ligitapor
dc.contributor.authorSalvetti, Massimopor
dc.contributor.authorSchlessinger, Davidpor
dc.contributor.authorSousa, Nunopor
dc.contributor.authorStefanadis, Christodoulospor
dc.contributor.authorStrait, Jamespor
dc.contributor.authorVan Daele, Carolinepor
dc.contributor.authorVilla, Isabelpor
dc.contributor.authorVlachopoulos, Charalambospor
dc.contributor.authorWitteman, Jacquelinepor
dc.contributor.authorXaplanteris, Panagiotispor
dc.contributor.authorNilsson, Peterpor
dc.contributor.authorLakatta, Edward G.por
dc.contributor.authorMARE Consortiumpor
dc.date.accessioned2015-02-02T12:29:10Z-
dc.date.available2015-02-02T12:29:10Z-
dc.date.issued2014-04-
dc.identifier.issn0021-9150por
dc.identifier.urihttps://hdl.handle.net/1822/33446-
dc.description.abstractSpecific clusters of metabolic syndrome (MetS) components impact differentially on arterial stiffness, indexed as pulse wave velocity (PWV). Of note, in several population-based studies participating in the MARE (Metabolic syndrome and Arteries REsearch) Consortium the occurrence of specific clusters of MetS differed markedly across Europe and the US. The aim of the present study was to investigate whether specific clusters of MetS are consistently associated with stiffer arteries in different populations. We studied 20,570 subjects from 9 cohorts representing 8 different European countries and the US participating in the MARE Consortium. MetS was defined in accordance with NCEP ATPIII criteria as the simultaneous alteration in >= 3 of the 5 components: abdominal obesity (W), high triglycerides (T), low HDL cholesterol (H), elevated blood pressure (B), and elevated fasting glucose (G). PWV measured in each cohort was "normalized" to account for different acquisition methods. MetS had an overall prevalence of 24.2% (4985 subjects). MetS accelerated the age-associated increase in PWV levels at any age, and similarly in men and women. MetS clusters TBW, GBW, and GTBW are consistently associated with significantly stiffer arteries to an extent similar or greater than observed in subjects with alteration in all the five MetS components - even after controlling for age, sex, smoking, cholesterol levels, and diabetes mellitus - in all the MARE cohorts. In conclusion, different component clusters of MetS showed varying associations with arterial stiffness (PWV). (C) 2014 Elsevier Ireland Ltd. All rights reserved.por
dc.description.sponsorshipNIH -National Institutes of Healthpor
dc.language.isoengpor
dc.publisherElsevierpor
dc.rightsrestrictedAccesspor
dc.subjectArterial stiffnesspor
dc.subjectCross-cultural comparisonpor
dc.subjectMetabolic syndromepor
dc.subjectPulse wave velocitypor
dc.titleArterial stiffness and influences of the metabolic syndrome : a cross-countries studypor
dc.typearticle-
dc.peerreviewedyespor
dc.relation.publisherversionhttp://www.elsevier.compor
sdum.publicationstatuspublishedpor
oaire.citationStartPage654por
oaire.citationEndPage660por
oaire.citationIssue2por
oaire.citationTitleAtherosclerosispor
oaire.citationVolume233por
dc.date.updated2015-01-30T15:41:41Z-
dc.identifier.doi10.1016/j.atherosclerosis.2014.01.041por
dc.identifier.pmid24561493por
dc.subject.wosScience & Technologypor
sdum.journalAtherosclerosispor
Aparece nas coleções:ICVS - Artigos em revistas internacionais / Papers in international journals

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