Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/33269

Full metadata record
DC FieldValueLanguage
dc.contributor.authorCorreia, Daniela M.por
dc.contributor.authorAzevedo, N. F.por
dc.contributor.authorVieira, M. J.por
dc.contributor.authorRocha, I.por
dc.date.accessioned2015-01-27T17:34:20Z-
dc.date.available2015-01-27T17:34:20Z-
dc.date.issued2010-10-11-
dc.identifier.citationCorreia, Daniela M.; Azevedo, N. F.; Vieira, M. J.; Rocha, I., System analysis of metabolism in Helicobacter pylori. Semana de Engenharia 2010. Guimarães, Portugal, Oct. 11-15, 2010.-
dc.identifier.urihttp://hdl.handle.net/1822/33269-
dc.description.abstractSystems biology integrates different levels of information for understanding biological systems. The availability of the genome sequence of Helicobacter pylori has allowed the construction of a genome-scale metabolic model for this organism. In order to study the behaviour of H. pylori and understand the mechanisms associated with infection using systems biology tools and controlled cultivation conditions, fermentations in a chemically defined medium were performed and several conditions were tested. The experimental data obtained were compared with simulated data generated by the existing model. The simultaneous use of both approaches allows to correct the in silico model and, on the other hand, to rationally adjust the medium components. The improvement of the genome-scale metabolic model will allow the identification of potential targets in order to design more effective drugs for the inactivation of H. pylori.por
dc.language.isoengpor
dc.rightsopenAccesspor
dc.subjectSystems biologypor
dc.subjectPhysiologypor
dc.subjectMetabolic networkspor
dc.titleSystem analysis of metabolism in Helicobacter pyloripor
dc.typeconferenceAbstract-
dc.peerreviewedyespor
dc.relation.publisherversionhttp://www3.dsi.uminho.pt/seeum2010/cd/por
dc.commentsCEB19769por
sdum.publicationstatuspublishedpor
oaire.citationConferenceDate11 a 15 out. 2010por
sdum.event.typeconferencepor
oaire.citationStartPage1por
oaire.citationEndPage2por
oaire.citationConferencePlaceGuimarães, Portugalpor
oaire.citationTitleSemana de Engenharia 2010por
dc.date.updated2015-01-19T09:25:10Z-
Appears in Collections:CEB - Resumos em Livros de Atas / Abstracts in Proceedings

Files in This Item:
File Description SizeFormat 
document_19769_1.pdf96,32 kBAdobe PDFView/Open

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID