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TitleKeratin/chitosan as novel grafts for peripheral nerve regeneration
Author(s)Carvalho, C. R.
Pedro, A. J.
Ng, K. W.
Neves, N. M.
Reis, R. L.
Oliveira, M.
KeywordsKeratin chitosan
Peripheral nerve regeneration
Issue dateJun-2014
PublisherJohn Wiley and Sons
JournalJournal of Tissue Engineering and Regenerative Medicine
CitationCarvalho C. R., Pedro J., Ng K. W., Neves N. M., Reis R. L., Oliveira M. Keratin/chitosan as novel grafts for peripheral nerve regeneration, Journal of Tissue Engineering and Regenerative Medicine, Vol. 8, Issue S1, pp. 434, doi:10.1002/term.1932, 2014
Abstract(s)For many years Peripheral Nerve Injuries (PNI) has been raising major concerns in regenerative medicine. Currently, the gold standard treatment for PNI is the autologous nerve grafting but it presents several drawbacks. Chitosan, along with keratin [1], for their good biocompatibility and physicochemical properties have been widely used as biomaterials in tissue engineering scaffolding. Many engineered biomaterials, natural or synthetic, have also been studied, but its poor architecture and lack of appropriate biological cues have been limiting nerve tissue regeneration [2]. In this study, an innovative combination of chitosan and keratin is obtained in order to create a novel nerve conduit (medical device) aimed at finding applications in the treatment of PNI.
AccessOpen access
Appears in Collections:3B’s - Resumos em livros de atas de conferências - indexados no ISI Web of Science

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