Utilize este identificador para referenciar este registo: http://hdl.handle.net/1822/32906

TítuloHigh-throughput screening for integrative biomaterials design : exploring advances and new trends
Autor(es)Oliveira, Mariana B.
Mano, J. F.
Palavras-chaveBiomaterials
High-throughput screening
DataOut-2014
RevistaTrends in Biotechnology
CitaçãoOliveira M. B., Mano J. F. High-throughput screening for integrative biomaterials design: exploring advances and new trends, Trends in Biotechnology, Vol. 32, Issue 12, pp. 627-636, doi:10.1016/j.tibtech.2014.09.009, 2014
Resumo(s)With the increasing need for biomaterials and tissue engineering alternatives, more accurate, rapid, and cost-saving methods and models to study biomaterial-cell interactions must be developed. We review the evolution of microarray platforms used for such studies in order to meet the criteria of complex tissue engineering biological environments. Particular aspects regarding biomaterials processing, data acquisition, and treatment are addressed. Apart from in vitroarray-based strategies, we also address emerging in vivo high-throughput approaches and their associated trends, such as the role of inflammation in regeneration. The up-scaling of high-throughput methods using single cell encapsulation systems is also explored. Possible limitations related to the use of such methods, such as spot-to-spot crosstalk, are also discussed.
Tipoarticle
URIhttp://hdl.handle.net/1822/32906
DOI10.1016/j.tibtech.2014.09.009
ISSN0167-7799
Versão da editorahttp://www.cell.com/trends/biotechnology/abstract/S0167-7799(14)00191-7
Arbitragem científicayes
AcessorestrictedAccess
Aparece nas coleções:3B’s - Artigos em revistas/Papers in scientific journals

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