Utilize este identificador para referenciar este registo: http://hdl.handle.net/1822/32900

TítuloAutomating the processing steps for obtaining bone tissue engineered substitutes : from imaging tools to bioreactors.
AutorCosta, P. F.
Martins, A.
Neves, N. M.
Gomes, Manuela E.
Reis, R. L.
Palavras-chave3D medical imaging
Additive manufacturing
Automation
Bioreactors
Computer-aided design
Tissue engineering
Data2014
EditoraMary Ann Liebert
CitaçãoCosta P. F., Martins A., Neves N. M., Gomes M. E., Reis R. L. Automating the processing steps for obtaining bone tissue engineered substitutes: from imaging tools to bioreactors., Tissue Engineering Part B: Reviews, Vol. 20, Issue 6, pp. 567-577, doi:10.1089/ten.teb.2013.0751, 2014
ResumoBone diseases and injuries are highly incapacitating and result in a high demand for tissue substitutes with specific biomechanical and structural features. Tissue engineering has already proven to be effective in regenerating bone tissue but has not yet been able to become an economically viable solution due to the complexity of the tissue which is very difficult to be replicated, eventually requiring the utilization of highly labour-intensive processes. Process automation is seen as the solution for mass production of cellularized bone tissue substitutes at an affordable cost by being able to reduce human intervention as well as reducing product variability. The combination of tools such as medical imaging, computer-aided fabrication and bioreactor technologies, which are currently used in tissue engineering, shows potential to generate automated production ecosystems which will in turn enable the generation of commercially available products with widespread clinical application.
Tipoarticle
URIhttp://hdl.handle.net/1822/32900
DOI10.1089/ten.teb.2013.0751
Arbitragem científicayes
AcessoopenAccess
Aparece nas coleções:3B’s - Artigos em revistas/Papers in scientific journals

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