Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/32708

TitleGardnerella vaginalis outcompetes 29 other bacterial species isolated from BV patients in an in vitro biofilm formation model
Author(s)Alves, Patrícia Maria
Castro, J.
Sousa, Cármen
Cereija, Tatiana Barros Reis
Cerca, Nuno
KeywordsBacterial vaginosis
Multi-species biofilm
Virulence determination
Issue date5-Mar-2014
PublisherUniversity of Chicago Press
JournalJournal of infectious diseases
CitationAlves, P.; Castro, Joana; Sousa, Cármen; Cereija, T. B.; Cerca, Nuno, Gardnerella vaginalis outcompetes 29 other bacterial species isolated from BV patients in an in vitro biofilm formation model. Journal of Infectious Diseases, 210(4), 593-596, 2014
Abstract(s)Despite the worldwide prevalence of bacterial vaginosis (BV), its etiology is still unknown. Although BV has been associated with the presence of biofilm, the ability of BV-associated bacteria to form biofilms is still largely unknown. Here, we isolated 30 BV-associated species and characterized their virulence, using an in vitro biofilm formation model. Our data suggests that Gardnerella vaginalis had the highest virulence potential, as defined by higher initial adhesion and cytotoxicity of epithelial cells, as well as the greater propensity to form a biofilm. Interestingly, we also demonstrated that most of the BV-associated bacteria had a tendency to grow as biofilms.
TypeArticle
URIhttp://hdl.handle.net/1822/32708
DOI10.1093/infdis/jiu131
ISSN0022-1899
e-ISSN1537-6613
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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