Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/32221

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dc.contributor.authorResende, T.por
dc.contributor.authorCorreia, Daniela M.por
dc.contributor.authorRocha, I.por
dc.date.accessioned2014-12-18T18:55:07Z-
dc.date.available2014-12-18T18:55:07Z-
dc.date.issued2013-
dc.identifier.citationResende, T.; Correia, Daniela M.; Rocha, I., Assignment of novel functions to Helicobacter pylori 26695’s genome. Advances in Intelligent Systems and Computing - New Perspectives in Information Systems and Technologies, Volume 2, 222, 29-36, 2013por
dc.identifier.isbn9783319005775por
dc.identifier.issn2194-5357por
dc.identifier.urihttp://hdl.handle.net/1822/32221-
dc.description.abstractHelicobacter pylori is a pathogenic bacterium that colonizes the human epithelia, causing duodenal and gastric ulcers as well as gastric cancer. The genome of H. pylori 26695 has been sequenced and annotated. In addition, two genome-scale metabolic models have been developed. In order to maintain accurate and relevant information on coding sequences (CDS) and to retrieve new information, the assignment of new functions to Helicobacter pylori 26695’s genes was performed. The use of software tools, on-line databases and an annotation pipeline for inspecting each gene allowed the attribution of validated E.C. numbers to metabolic genes, and the assignment of 177 new functions to the CDS of this bacterium. This information provides relevant biological information for the scientific community dealing with this organism and can be used as the basis for a new metabolic model reconstruction.por
dc.language.isoengpor
dc.publisherSpringerpor
dc.relationinfo:eu-repo/grantAgreement/FCT/5876-PPCDTI/104235/PT-
dc.rightsopenAccesspor
dc.subjectHelicobacter pyloripor
dc.subjectGenome annotationpor
dc.subjectMetabolic functionspor
dc.subjectGenome-Scale Reconstructionpor
dc.titleAssignment of novel functions to Helicobacter pylori 26695’s genomepor
dc.typebookPart-
dc.peerreviewedyespor
dc.relation.publisherversionhttp://www.springer.com/series/11156por
dc.commentsCEB15027por
sdum.publicationstatuspublishedpor
oaire.citationStartPage29por
oaire.citationEndPage36por
oaire.citationVolume222por
dc.date.updated2014-12-01T11:06:29Z-
dc.identifier.essn2194-5365-
dc.identifier.doi10.1007/978-3-319-00578-2_5por
sdum.journalAdvances in Intelligent Systems and Computingpor
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