Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/32115

TitleAntifungal activity of phenolic compounds identified in flowers from the North Eastern Portugal against Candida species
Author(s)Alves, Carlos
Ferreira, Isabel C. F. R.
Barros, Lillian
Silva, Sónia Carina
Azeredo, Joana
Henriques, Mariana
Keywordsantifungal effect
biofilms
Candida species
medicinal flowers
phenolic compounds
Issue date2014
PublisherFuture Medicine
JournalFuture Microbiology
CitationAlves, Carlos; Ferreira, Isabel; Barros, Lillian; Silva, Sónia Carina; Azeredo, Joana; Henriques, Mariana, Antifungal activity of phenolic compounds identified in flowers from the North Eastern Portugal against Candida species. Future Microbiology, 9(2), 139-146, 2014
Abstract(s)Aim: To evaluate the antifungal effect of gallic acid, catechin, luteolin and quercetin, phenolic compounds identified from flowers of the North Eastern Portugal, against Candida planktonic and biofilm cells. Materials and Methods: The minimal inhibitory concentrations (MIC) were determined in Candida planktonic cells and the effect of phenolic compounds on Candida biofilms was assessed through quantification by colony forming units (CFUs). Results: MIC values demonstrated that gallic acid presented the highest effect against the all Candida species. Catechin showed a similar effect against C. albicans ATCC 90028cells. Additionally, gallic acid and quercetin had demonstrated only a minimum effect against Candida species biofilms. Conclusions: Gallic acid affected the growth of the different planktonic Candida species in all concentrations used, still catechin showed a similar effect against C. albicans ATCC 90028and C. glabrata ATCC 2001cells.Additionally, only gallic acid and quercetin demonstrated a slight effect against all Candida species biofilms.
TypeArticle
URIhttp://hdl.handle.net/1822/32115
DOI10.2217/FMB.13.147
ISSN1746-0913
e-ISSN1746-0921
Publisher versionwww.ncbi.nlm.nih.gov/pubmed/24571069
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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