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TitleCandida glabrata : a review of its features and resistance
Author(s)Rodrigues, Célia F.
Silva, Sónia Carina
Henriques, Mariana
Issue date2014
JournalEuropean Journal of Clinical Microbiology and Infectious Diseases
CitationRodrigues, Célia F.; Silva, Sónia Carina; Henriques, Mariana, Candida glabrata: a review of its features and resistance. European Journal of Clinical Microbiology & Infectious Diseases, 33(5), 673-688, 2014
Abstract(s)Candida species belong to the normal microbiota of the oral cavity and gastrointestinal and vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous overgrowth to bloodstream infections. Once believed to be non-pathogenic, Candida glabrata was rapidly blamable for many human diseases. Year after year, these pathological circumstances are more recurrent and problematic to treat, especially when patients reveal any level of immunosuppression. These difficulties arise from the capacity of C. glabrata to form biofilms and also from its high resistance to traditional antifungal therapies. Thus, this review intends to present an excerpt of the biology, epidemiology, and pathology of C. glabrata, and detail an approach to its resistance mechanisms based on studies carried out up to the present.
AccessOpen access
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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