Utilize este identificador para referenciar este registo: http://hdl.handle.net/1822/31463

TítuloEvaluation of macroporous and microporous carriers for cho-k1 cell growth and mab production
Autor(es)Rodrigues, E.
Costa, A. R.
Data2011
CitaçãoRodrigues, E.; Costa, A. R.; Oliveira, Rosário; Azeredo, Joana; Henriques, Mariana, Evaluation of macroporous and microporous carriers for cho-k1 cell growth and mab production. Semana da Escola de Engenharia 2011 - Uma Escola a Reinventar o Futuro. Guimarães, Portugal, Oct. 24-27, 2011. ISBN: 978-972-8692-61-2
Resumo(s)Large-scale biopharmaceutical production commonly relies on suspension cell cultures that provide higher yields than adherent cultures. However, most mammalian cells grow adherently and need to be adapted to suspension, which is not always simple or feasible. Microcarrier culture introduces new possibilities and allows the practical high yield culture of anchorage-dependent cells in suspension systems. In these systems, cells grow as monolayers on the surface of the microcarriers, which are usually in suspension in the culture medium by gentle rocking. The aim of the study was to evaluate, compare and optimize the use of microcarriers for the growth and antibody production by CHO-K1 cells.
TipoconferenceAbstract
URIhttp://hdl.handle.net/1822/31463
ISBN978-972-8692-61-2
Versão da editorawww3.dsi.uminho.pt/seeum2011/CD
Arbitragem científicayes
AcessoopenAccess
Aparece nas coleções:CEB - Resumos em Livros de Atas / Abstracts in Proceedings

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