Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/31108

TitleLayer-by-layer deposition of antimicrobial polymers on cellulosic fibers : a new strategy to develop bioactive textiles
Author(s)Gomes, Ana P.
Mano, J. F.
Queiroz, J. A.
Gouveia, I. C.
KeywordsAlginate
Chitosan
Cotton
JIS L 1902
LbL
Issue dateOct-2013
PublisherJohn Wiley and Sons
JournalPolymers for Advanced Technologies
Abstract(s)In recent years, there has been an increase of infectious diseases caused by different microorganisms and the development of antibiotic resistance. In this way, the search for new and efficient antibacterial materials is imperative. The main polysaccharides currently used in the biomedical and pharmaceutical domains are chitin and its derivative chitosan (CH) and alginates (ALG). In this study, a simple technique of Layer by Layer (LbL) of applying polycation CH and polyanion ALG was used to prepare CH/ALG multilayers on cotton samples via the electrostatic assembly with success. The CH/ALG cotton samples (functionalized) were investigated for their antibacterial properties towards Staphylococcus aureus and Klebsiella pneumonia using the international standard method JIS L 1902:2002. The antibacterial activity of the functionalized samples was tested in terms of bacteriostatic and bactericidal activity, and results showed that the samples exhibited a bacteriostatic effect on the two bacteria tested, as expected. In addition, samples with five layers (CH/ALG/CH/ALG/CH) were more effective in inhibiting bacterial growth. This new coating for cellulosic fibers is a new strategy and may open new avenues for the development of antimicrobial polymers with potential application in health-care field.
TypeArticle
URIhttp://hdl.handle.net/1822/31108
DOI10.1002/pat.3176
ISSN1099-1581 (online)
Publisher versionhttp://onlinelibrary.wiley.com/doi/10.1002/pat.3176/abstract
Peer-Reviewedyes
AccessOpen access
Appears in Collections:3B’s - Artigos em revistas/Papers in scientific journals


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