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|Title:||Magnetoliposomes based on nickel/silica core/shell nanoparticles : synthesis and characterization|
|Author(s):||Rodrigues, Ana Rita Oliveira|
Gomes, Isabel Alexandra Domingues Tarroso
Almeida, B. G.
Araújo, João P.
Castanheira, Elisabete M. S.
Coutinho, Paulo J. G.
|Journal:||Materials chemistry and physics|
|Abstract(s):||In the present work, nickel magnetic nanoparticles with diameters lower than 100nm, with and without silica shell, were synthesized by microheterogeneous templating. The magnetic properties of the nanoparticles show a typical ferromagnetic behavior with a coercive field of 80Oe. Dry magnetoliposomes (DMLs) with diameter between 58nm and 76nm were obtained from the synthesis of nanoparticles in the presence of a lipid or surfactant layer, and aqueous magnetoliposomes (AMLs) were obtained by encapsulation of the nanoparticles in liposomes. FRET (Förster resonance energy transfer) experiments were performed to study the non-specific interactions between aqueous magnetoliposomes and giant unilamellar vesicles (GUVs), as models of cell membranes. It was possible to detect membrane fusion between GUVs and AMLs containing both NBD-C6-HPC (donor) and the dye Nile Red (acceptor).|
|Description:||"Available online 18 September 2014"|
|Appears in Collections:||CDF - FAMO - Artigos/Papers (with refereeing)|
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