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TitleFunctionalized nanoparticles for intracellular drug delivery and cell-tracking
Author(s)Oliveira, Joaquim M.
KeywordsBiomedical applications
Top down fabrication
Issue dateOct-2014
CitationOliveira J. M. Functionalized nanoparticles for intracellular drug delivery and cell-tracking, Polaris 2nd Workshop, 2014
Abstract(s)Cell- and tissue-engineering have greatly benefited from huge developments on the nanotechnology field. Important achievements include not only the increasing number of nanoparticles (NP’s) that have synthesized but also from the innumerous possibilities for tuning its biological and physicochemical properties by means of surface engineering. Our group has been proposing the functionalization and coating of different nanosystems (e.g. dendrimer-based NP’s and gold nanorods) as a strategy to improve biocompatibility, enhance NP’s uptake by cells and intracellular drug release, and allow investigating cell fate. The developed surface engineering strategies represent the future of therapeutic approaches envisioning the control of stem cells functions in vitro and in vivo, which can open new possibilities for treating different neurodegenerative and musculoskeletal diseases/disabilities.
Publisher version
AccessOpen access
Appears in Collections:3B’s - Resumos em livros de atas de conferências - indexados no ISI Web of Science

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