Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/28182
Título: | Chitosan/chondroitin sulfate multilayers as supports for calcium phosphate biomineralization |
Autor(es): | Leite, Álvaro J. Sher, Praveen Mano, J. F. |
Palavras-chave: | Multilayer structure Biomimetic Biomaterials Nanocomposites |
Data: | Abr-2014 |
Editora: | Elsevier 1 |
Revista: | Materials letters |
Resumo(s): | We investigated the interaction of natural derived macromolecular multilayers with calcium and phosphate ions entirely processed using the layer-by-layer (LbL) technique. A nanostructured multilayer component, with 5 or 10 bilayers, was first produced using weak polyelectrolyte biopolymers, chitosan and chondroitin sulfate. This was followed by sequential passing of solutions containing Ca2+andPO43−over the multilayers. QCM-D, SEM and EDX results conferred the formation of calcium phosphate (CaP) over the polyelectrolyte multilayers. Initiation of precipitation was observed earlier in the 10 bilayers coating than in the 5 bilayers one. These results indicate the potential of multilayers to trap ions, as a biomimetic approach that can be used to induce CaP precipitation. This could enable the preparation of more performant bioactive composite biomaterials for orthopedic applications, including in bone tissue engineering. |
Tipo: | Artigo |
Descrição: | "Available online 24 January 2014" |
URI: | https://hdl.handle.net/1822/28182 |
DOI: | 10.1016/j.matlet.2014.01.099 |
ISSN: | 0167-577X |
Versão da editora: | http://dx.doi.org/10.1016/j.matlet.2014.01.099 |
Arbitragem científica: | yes |
Acesso: | Acesso restrito UMinho |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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17903-10.1016:j.matlet.2014.01.099.pdf Acesso restrito! | 1,36 MB | Adobe PDF | Ver/Abrir |