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|Title:||Synthesis and photophysical studies of new pyrenylamino acids|
Castanheira, Elisabete M. S.
Schellenberg, Peter Michael
Ferreira, Paula M. T.
Monteiro, Luís S.
|Abstract(s):||Two new pyrenylamino acid derivatives were synthesized from beta-bromodehydroalanine derivatives in good yields using addition and elimination reactions. The photophysical properties of the two new pyrenylamino acids were studied in several solvents. Steady-state and time-resolved fluorescence measurements revealed that the bipyrenylamino acid undergoes excimer formation, this process being solvent dependent. Rate constants for excimer formation and dissociation were calculated. The monopyrenylamino acid exhibits a photophysical behavior similar to that of pyrene, including the sensitivity to solvent polarity. The results point to a potential use of these new pyrenyl derivatives as fluorescent probes for peptides and proteins.|
|Appears in Collections:||CDF - FAMO - Artigos/Papers (with refereeing)|
CDQuim - Artigos (Papers)
Files in This Item:
|2013-Pyrenylamino acids_Tetrahedron.pdf||Documento principal||914,9 kB||Adobe PDF||View/Open|
|Supplementary data_Tet2013.pdf||Informação suplementar||139,87 kB||Adobe PDF||View/Open|