Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/25591
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Silva, Simone Santos | - |
dc.contributor.author | Duarte, Ana Rita C. | - |
dc.contributor.author | Oliveira, Joaquim M. | - |
dc.contributor.author | Mano, J. F. | - |
dc.contributor.author | Reis, R. L. | - |
dc.date.accessioned | 2013-10-08T14:25:54Z | - |
dc.date.available | 2013-10-08T14:25:54Z | - |
dc.date.issued | 2013-08 | - |
dc.date.submitted | 2013-09 | - |
dc.identifier.issn | 0883–9115 | por |
dc.identifier.uri | https://hdl.handle.net/1822/25591 | - |
dc.description.abstract | An alternative, green method was used to develop chitin-based biocomposite (ChHA) materials by an integrated strategy using ionic liquids, supercritical fluid drying, and salt leaching. ChHA matrices were produced by dissolving chitin in 1-butyl-methylimidazolium acetate along with salt and/or hydroxyapatite particles and then subsequent drying. The ChHA composite formed had a heterogeneous porous microstructure with 65%–85% porosity and pore sizes in the range of 100–300 µm. The hydroxyapatite was found to be well distributed within the composite structures and had a positive effect in the viability and proliferation of osteoblast-like cells, in vitro. Our findings indicate that these ChHA matrices have potential applications in bone tissue engineering. | por |
dc.description.sponsorship | Simone S. Silva and Miguel Oliveira received financial support from the Portuguese Foundation for Science and Technology-FCT (Grant SFRH/BPD/45307/2008 and SFRH/BPD/21786/2009, respectively), "Fundo Social Europeu"-FSE, and "Programa Diferencial de Potencial Humano-POPH." This work was partially supported by the FEDER through POCTEP 0330_IBEROMARE_1_P and European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement no. KBBE-2010-266033 (project SPECIAL). | por |
dc.language.iso | eng | por |
dc.publisher | SAGE | por |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/266033 | - |
dc.rights | openAccess | por |
dc.subject | Chitin | por |
dc.subject | Hydroxyapatite | por |
dc.subject | Ionic liquids | por |
dc.subject | Supercritical fluid technology | por |
dc.subject | scaffold pores sizing | por |
dc.subject | Composites | por |
dc.subject | salt leaching | por |
dc.subject | controlled pore sizes | por |
dc.title | Alternative methodology for chitin/hydroxyapatite composites using ionic liquids and supercritical fluid technology | por |
dc.type | article | - |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://jbc.sagepub.com/content/28/5/481 | por |
dc.comments | http://www.3bs.uminho.pt/node/17661 | por |
sdum.publicationstatus | published | por |
oaire.citationStartPage | 481 | por |
oaire.citationEndPage | 491 | por |
oaire.citationIssue | 5 | por |
oaire.citationTitle | Journal of Bioactive and Compatible Polymers | por |
oaire.citationVolume | 28 | por |
dc.date.updated | 2013-09-24T15:29:47Z | - |
dc.identifier.doi | 10.1177/0883911513501595 | - |
dc.subject.wos | Science & Technology | por |
sdum.journal | Journal of Bioactive and Compatible Polymers | por |
Aparece nas coleções: | 3B’s - Artigos em revistas/Papers in scientific journals |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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17661-Journal of Bioactive and compatible polymers_ Silva et al 2013.pdf | 1,32 MB | Adobe PDF | Ver/Abrir |