Utilize este identificador para referenciar este registo: http://hdl.handle.net/1822/25591

TítuloAlternative methodology for chitin/hydroxyapatite composites using ionic liquids and supercritical fluid technology
Autor(es)Silva, Simone Santos
Duarte, Ana Rita C.
Oliveira, Joaquim M.
Mano, J. F.
Reis, R. L.
Ionic liquids
Supercritical fluid technology
scaffold pores sizing
salt leaching
controlled pore sizes
RevistaJournal of Bioactive and Compatible Polymers
Resumo(s)An alternative, green method was used to develop chitin-based biocomposite (ChHA) materials by an integrated strategy using ionic liquids, supercritical fluid drying, and salt leaching. ChHA matrices were produced by dissolving chitin in 1-butyl-methylimidazolium acetate along with salt and/or hydroxyapatite particles and then subsequent drying. The ChHA composite formed had a heterogeneous porous microstructure with 65%–85% porosity and pore sizes in the range of 100–300 µm. The hydroxyapatite was found to be well distributed within the composite structures and had a positive effect in the viability and proliferation of osteoblast-like cells, in vitro. Our findings indicate that these ChHA matrices have potential applications in bone tissue engineering.
Versão da editorahttp://jbc.sagepub.com/content/28/5/481
Arbitragem científicayes
Aparece nas coleções:3B’s - Artigos em revistas/Papers in scientific journals

Ficheiros deste registo:
Ficheiro Descrição TamanhoFormato 
17661-Journal of Bioactive and compatible polymers_ Silva et al 2013.pdf1,32 MBAdobe PDFVer/Abrir

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu Currículo DeGóis