Utilize este identificador para referenciar este registo: http://hdl.handle.net/1822/25167

TítuloPorous hydrogels from shark skin collagen crosslinked under dense carbon dioxide atmosphere
Autor(es)Silva, S. P.
Moreira-Silva, J.
Silva, Tiago H.
Perez-Martin, R. I.
Sotelo, C. G.
Mano, J. F.
Duarte, Ana Rita C.
Reis, R. L.
Marine biotechnolgoy
Supercritical fluids
Tissue engineering
marine biotechnology
RevistaMacromolecular Bioscience
Resumo(s)The possibility to fabricate marine collagen porous structures crosslinked with genipin under high pressure carbon dioxide is investigated. Collagen from shark skin is used to prepare prescaffolds by freeze-drying. The poor stability of the structures and low mechanical properties require crosslinking of the structures. Under dense CO2 atmosphere, crosslinking of collagen pre-scaffolds is allowed for 16 h. Additionally, the hydrogels are foamed and the scaffolds obtained present a highly porous structure. In vitro cell culture tests performed with a chondrocyte-like cell line show good cell adherence and proliferation, which is a strong indication of the potential of these scaffolds to be used in tissue cartilage tissue engineering.
Versão da editorahttp://onlinelibrary.wiley.com/doi/10.1002/mabi.201300228/abstract
Arbitragem científicayes
Aparece nas coleções:3B’s - Artigos em revistas/Papers in scientific journals

Ficheiros deste registo:
Ficheiro Descrição TamanhoFormato 
17649-Pouros hydrogels from shark skin collagen_2013.pdf703,72 kBAdobe PDFVer/Abrir

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu Currículo DeGóis