Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/24983

TitleExercise intervention in treatment-resistant major depressive disorder : benefits of accelerometer monitoring
Author(s)Mota-Pereira, Jorge
Ribeiro, José Carlos
Fonte, Daniela
Carvalho, Serafim
Ramos, Joaquim
Silvério, Jorge Manuel Amaral
KeywordsAccelerometer
Walking
Exercise
Physical activity
Depression
Major depression
Issue date2013
PublisherNova Science Publishers
Abstract(s)Although there are several reports on the benefits of exercise on Major Depressive Disorder, none has monitored these exercise programs with accelerometers. We have conducted a 12 week home based moderate intensity exercise program in 33 treatmentresistant Major Depressive Disorder patients and, based on accelerometer data, determined compliance, exercise patterns and relationship between time spent in MVPA, response to treatment and Quality of Life. Patients were diagnosed according to DSM-IV criteria, and, from 150 initially screened, 33 met study criteria and were included. Four patients were excluded due to non-compliance/drop-out, thus a total of 29 patients finished the study. Patients were randomized either to a moderate intensity exercise program, which consisted of 30-45 min/day walks, 5 days/week, for 12 weeks, plus usual pharmacotherapy (N=22) or regular daily activities plus usual pharmacotherapy (N=11). All participants wore an ActiGraph® GT1M accelerometer during the 12 weeks. Moderate to very vigorous physical activity (MVPA), HAMD17, BDI, GAF, CGI-S, WHOQOL-Bref and SF-36 were assessed. Results show a trend for increasing time spent in MVPA from no response to response and remission (p = 0.028), and medium to strong correlations between time spent in MVPA and better depression and functioning parameters. There was also a trend for increasing time spent in MVPA and improvement of some QoL domains, namely WHOQOL-Bref Physical domain and SF-36 Physical Functioning and General Health Domains (p < 0.05). Participants showed preference for exercising on weekdays and on specific periods of the day (p < 0.05). Therefore, we suggest that future implementation of effective exercise augmentation therapy programs in MDD patients should consider objective measures that allow the quantification of exercise and assessment of exercise patterns.
TypeBook part
URIhttp://hdl.handle.net/1822/24983
ISBN978-1-62618-578-4
Publisher versionhttps://www.novapublishers.com/catalog/product_info.php?products_id=43053&osCsid=dec2a98da19344b8804ef2eb893f1c0a
Peer-Reviewedyes
AccessOpen access
Appears in Collections:CIPsi - Livros e Capítulos de Livros

Files in This Item:
File Description SizeFormat 
978-1-62618-578-4_ch5.pdf330,38 kBAdobe PDFView/Open

Partilhe no FacebookPartilhe no TwitterPartilhe no DeliciousPartilhe no LinkedInPartilhe no DiggAdicionar ao Google BookmarksPartilhe no MySpacePartilhe no Orkut
Exporte no formato BibTex mendeley Exporte no formato Endnote Adicione ao seu ORCID