Please use this identifier to cite or link to this item:
http://hdl.handle.net/1822/24437| Title: | Bioactive silicate nanoplatelets for osteogenic differentiation of human mesenchymal stem cells |
| Author(s): | Gaharwar, Akhilesh K. Mihaila, Silvia M. Swami, A. Patel, A. Sant, A. Reis, R. L. Marques, A. P. Gomes, Manuela E. Khademhosseini, Ali |
| Keywords: | Osteogenic differentiation Osteoinductive Silicate nanoplatelets Stem cells synthetic clay laponite nanoparticles human mesenchymal stem cells tissue engineering |
| Issue date: | May-2013 |
| Publisher: | Wiley-VCH Verlag |
| Journal: | Advanced Materials |
| Abstract(s): | Novel silicate nanoplatelets that induce osteogenic differentiation of human mesenchymal stem cells (hMSCs) in the absence of any osteoinductive factor are reported. The presence of the silicate triggers a set of events that follows the temporal pattern of osteogenic differentiation. These findings underscore the potential applications of these silicate nanoplatelets in designing bioactive scaffolds for musculoskeletal tissue engineering. |
| Type: | Article |
| URI: | http://hdl.handle.net/1822/24437 |
| DOI: | 10.1002/adma.201300584 |
| ISSN: | 1521-4095 (on-line) |
| Publisher version: | http://onlinelibrary.wiley.com/doi/10.1002/adma.201300584/abstract |
| Peer-Reviewed: | yes |
| Access: | Restricted access (UMinho) |
| Appears in Collections: |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 17542-Silvia Mihaila_AdvMat_Bioactive Silicate Nanoplatelets for Osteogenic Differentiation of Human Mesenchymal Stem Cells.pdf Restricted access | 1,62 MB | Adobe PDF | View/Open |
