Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/22844
Registo completo
Campo DC | Valor | Idioma |
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dc.contributor.author | Ribeiro, C. | - |
dc.contributor.author | Moreira, Susana Margarida Gomes | - |
dc.contributor.author | Correia, Vítor | - |
dc.contributor.author | Sencadas, Vítor João Gomes Silva | - |
dc.contributor.author | Rocha, J. G. | - |
dc.contributor.author | Gama, F. M. | - |
dc.contributor.author | Gómez Ribelles, J. L. | - |
dc.contributor.author | Lanceros-Méndez, S. | - |
dc.date.accessioned | 2013-01-29T11:00:48Z | - |
dc.date.available | 2013-01-29T11:00:48Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 2046-2069 | por |
dc.identifier.uri | https://hdl.handle.net/1822/22844 | - |
dc.description.abstract | This work reports on the influence of the polarization of electroactive poly(vinylidene fluoride), PVDF, on the biological response of cells cultivated under static and dynamic conditions. Non-poled and "poled +" β-PVDF with and without titanium layer were thus prepared. Thin titanium layer was deposited on PVDF films in order to get a more homogeneous surface charge. MC3T3-E1 osteoblast cell culture 10 exhibited different responses in the presence of PVDF films. The positively charged β-PVDF films promote higher osteoblast adhesion and proliferation, which is higher under dynamic conditions on poled samples, showing that the surface charge under mechanical stimulation improves the osteoblast growth. Therefore, electroactive membranes and scaffolds can provide the necessary electrical stimuli for the growth and proliferation of specific cells. | por |
dc.description.sponsorship | This work is funded by FEDER funds through the "Programa Operacional Factores de Competitividade-COMPETE" and by national funds by FCT-Fundacao para a Ciencia e a Tecnologia, project reference NANO/NMed-SD/0156/2007. C. R. thanks the INL for a PhD grant. V.S. thanks the FCT for the SFRH/BPD/63148/2009 grants. Authors thank Armando Ferreira and Filipe Vaz for the help with titanium deposition on PVDF films.JLGR acknowledge the support of the Spanish Ministry of Education through project No. MAT2010-21611-C03-01 (including the FEDER financial support) and project EUI2008-00126. | por |
dc.language.iso | eng | por |
dc.publisher | Royal Society of Chemistry | por |
dc.rights | restrictedAccess | por |
dc.title | Enhanced proliferation of pre-osteoblastic cells by dynamic piezoelectric stimulation | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://dx.doi.org/10.1039/c2ra21841k | - |
sdum.publicationstatus | published | por |
oaire.citationStartPage | 11504 | por |
oaire.citationEndPage | 11509 | por |
oaire.citationIssue | 30 | por |
oaire.citationTitle | RSC Advances | por |
oaire.citationVolume | 2 | por |
dc.identifier.doi | 10.1039/c2ra21841k | - |
dc.subject.wos | Science & Technology | por |
sdum.journal | RSC Advances | por |
Aparece nas coleções: | CAlg - Artigos em revistas internacionais / Papers in international journals CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series CDF - FCD - Artigos/Papers (with refereeing) |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
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RSC adv_F.pdf Acesso restrito! | 692,79 kB | Adobe PDF | Ver/Abrir |