Utilize este identificador para referenciar este registo:
https://hdl.handle.net/1822/22515
Registo completo
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Oliveira, Carla Cristina Marques de | - |
dc.contributor.author | Guimarães, Pedro M. R. | - |
dc.contributor.author | Domingues, Lucília | - |
dc.date.accessioned | 2013-01-10T17:26:31Z | - |
dc.date.available | 2013-01-10T17:26:31Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0734-9750 | por |
dc.identifier.uri | https://hdl.handle.net/1822/22515 | - |
dc.description.abstract | β-Galactosidases (EC 3.2.1.23) constitute a large family of proteins that are known to catalyze both hydrolytic and transgalactosylation reactions. The hydrolytic activity has been applied in the food industry for decades for reducing the lactose content in milk, while the transgalactosylation activity has been used to synthesize galacto-oligosaccharides and galactose containing chemicals in recent years. The main focus of this review is on the expression and production of Aspergillus niger, Kluyveromyces lactis and bacterial β-galactosidases in different microbial hosts. Furthermore, emphasis is given on the reported applications of the recombinant enzymes. Current developments on novel β-galactosidases, derived from newly identified microbial sources or by protein engineering means, together with the use of efficient recombinant microbial production systems are converting this enzyme into a relevant synthetic tool. Thermostable β-galactosidases (cold-adapted or thermophilic) in addition to the growing market for functional foods will likely redouble its industrial interest. | por |
dc.description.sponsorship | C. Oliveira and P. M. R. Guimaraes acknowledge support from Fundacao para a Ciencia e a Tecnologia (FCT), Portugal (grants SFRH/BDP/63831/2009 and SFRH/BDP/44328/2008, respectively). | por |
dc.language.iso | eng | por |
dc.publisher | Elsevier 1 | por |
dc.rights | openAccess | por |
dc.subject | Recombinant β-galactosidase | por |
dc.subject | Thermophilic enzymes | por |
dc.subject | Cold-adapted enzymes | por |
dc.subject | Recombinant microbial systems | por |
dc.subject | Transgalactosylation activity | por |
dc.subject | Milk lactose hydrolysis | por |
dc.subject | Whey bioremediation | por |
dc.subject | Recombinant beta-galactosidase | por |
dc.title | Recombinant microbial systems for improved β-galactosidase production and biotechnological applications | por |
dc.type | article | por |
dc.peerreviewed | yes | por |
dc.relation.publisherversion | http://www.sciencedirect.com/ | por |
sdum.publicationstatus | published | por |
oaire.citationStartPage | 600 | por |
oaire.citationEndPage | 609 | por |
oaire.citationIssue | 6 | por |
oaire.citationTitle | Biotechnology Advances | por |
oaire.citationVolume | 29 | por |
dc.identifier.doi | 10.1016/j.biotechadv.2011.03.008 | por |
dc.identifier.pmid | 21514372 | por |
dc.subject.wos | Science & Technology | por |
sdum.journal | Biotechnology Advances | por |
Aparece nas coleções: | CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series |
Ficheiros deste registo:
Ficheiro | Descrição | Tamanho | Formato | |
---|---|---|---|---|
1-s2.0-S0734975011000437-main.pdf | 648,75 kB | Adobe PDF | Ver/Abrir |