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TitleLactate-induced il-8 pathway in endothelial cells-letter
Author(s)Pinheiro, Céline
Longatto Filho, Adhemar
Nogueira, Rosete
Schmitt, Fernando C.
Baltazar, Fátima
Issue dateApr-2012
PublisherAmerican Association for Cancer Research
JournalCancer Research
Abstract(s)Vegran and colleagues proposed a model in which the lactate released from tumor cells through MCT4 would be taken up by endothelial cells via the MCT1 transporter and stimulate angiogenesis, using human umbilical vein endothelial cells (HUVECs) as model of tumor endothelial cells. By analyzing a total of 505 cases of human tumor samples immunostained for MCT1, we do not confirm plasma membrane expression of MCT1 in the endothelial cells of tumor-associated vessels.
TypeLetter to the editor
Publisher version
AccessOpen access
Appears in Collections:ICVS - Artigos em Revistas Internacionais com Referee

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