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TitleHigh yielding synthesis of heterocyclic beta-substituted alanine derivatives
Author(s)Ferreira, Paula M. T.
Maia, Hernâni L. S.
Monteiro, Luís S.
Issue date1999
JournalTetrahedron Letters
Citation"Tetrahedron letters". 40 (1999) 4099-4102.
Abstract(s)Heterocyclic beta-substituted alanine derivatives such as beta-(pyrazol-1-yl) and beta-(1,2,4-triazol-1-yl)-alanine are synthesized in high yields by a Michael addition of heterocyclic nucleophiles to N,N-bis(tert-butyloxycarbonyl)-dehydroalanine methyl ester, using mild reaction conditions and simple work-up procedures.
AccessOpen access
Appears in Collections:CDQuim - Artigos (Papers)

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