Please use this identifier to cite or link to this item: http://hdl.handle.net/1822/1754

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dc.contributor.authorMota, M.-
dc.contributor.authorTeixeira, J. A.-
dc.contributor.authorYelshin, Alexander-
dc.date.accessioned2005-05-24T10:37:47Z-
dc.date.available2005-05-24T10:37:47Z-
dc.date.issued2001-
dc.identifier.citation“Biotechnology progress”. 17:5 (2001) 860-865.eng
dc.identifier.issn8756-7938por
dc.identifier.urihttp://hdl.handle.net/1822/1754-
dc.description.abstractDiffusion in pure gels and gels with immobilized cells was analyzed. A model of diffusion assuming a homogeneous cell distribution in gel was improved by introducing a tortuosity value. By theoretical analysis and numerical modeling it was shown that the tortuosity of a gel with immobilized cells is the product of two factors: (1) tortuosity generated by the cells, Tc, and (2) tortuosity of the gel matrix, Tg, both variables being a function of cell volume fraction. Total tortuosity is thus T=TcTg. On the basis of this approach, it was possible to analyze diffusivity data for gels with immobilized cells. It was shown that, in these systems, the diffusivity = De/D0 is a complex function of (1) diffusivity in the gel, and (2) diffusivity in immobilized cells. The developed model allowed for the description of the dependence of De/D0 on fi_c. Comparison with numerous published experimental data showed a good fit. Observed deviations might be explained by nonhomogeneous cell distributions inside the gel matrix.eng
dc.description.sponsorshipPRAXIS XXI - BBC/6440/95.por
dc.language.isoengeng
dc.publisherAmerican Chemical Societyeng
dc.publisherAmerican Institute of Chemical Engineers-
dc.rightsopenAccesseng
dc.titleImmobilized particles in gel matrix-type porous media: homogeneous porous media modeleng
dc.typearticleeng
dc.peerreviewedyeseng
oaire.citationStartPage860por
oaire.citationEndPage865por
oaire.citationIssue5por
oaire.citationVolume17por
dc.identifier.doi10.1021/bp010064tpor
dc.identifier.pmid11587575por
dc.subject.wosScience & Technologypor
sdum.journalBiotechnology Progresspor
Appears in Collections:CEB - Publicações em Revistas/Séries Internacionais / Publications in International Journals/Series

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